Intracellular cholesterol biosynthesis in enchondroma and chondrosarcoma
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چکیده
منابع مشابه
Enchondroma versus Low-Grade Chondrosarcoma in Appendicular Skeleton: Clinical and Radiological Criteria
Objectives. To determine the validity of clinical and radiological features of enchondroma and low grade chondrosarcoma, and contrast the biopsy results with the clinical diagnosis based on the history and imaging. Material and Method. The study included 96 patients with cartilage type lesions suggestive of an enchondroma (E) or an low grade chondrosarcoma (LGC) according to the clinical and im...
متن کاملMast cells density in fibrotic capsule of enchondroma and well-differentiated chondrosarcoma: a method for histopathologic differentiation
Background: An enchondroma is a benign and a well-differentiated chondrosarcoma is an invasive chondroid tumor with high recurrence potential. In spite of biologic differences, these two tumors have very similar histopathologic appearance. It has been shown that the biologic nature of the connective tissue around benign and malignant tumors varies in the number of mast cells. The aim of this s...
متن کاملHistopathologic Differentiation between Enchondroma and Well-differentiated Chondrosarcoma: Evaluating the Efficacy of Diagnostic Histologic Structures
BACKGROUND AND AIMS Well-differentiated chondrosarcoma and enchondroma are similar in histopathologic aspects; therefore, special methods should be used to make a distinction between these benign and malignant tumors. The aim of this study was to evaluate the efficacy of a histopathologic method in the long-term follow-up for differentiating these lesions. MATERIALS AND METHODS The medical re...
متن کاملFrom the Archives of the AFIP Enchondroma versus Chondrosarcoma in the Appendicular Skeleton : Differentiating Features 1
#{149} Be familiar with the radiologic manifestations that allow differentiation of the majority of enchondromas and intramedullary chondrosarcomas affecting the appendicular skeleton. Distinction of enchondroma versus intramedullary chondrosarcoma a!fecting the appendicular skeleton (proximal to the metacarpals and metatarsals) is a frequent diagnostic dilemma. The authors studied a large seri...
متن کاملIdentification of novel biomarker candidates for immunohistochemical diagnosis to distinguish low-grade chondrosarcoma from enchondroma.
Chondrosarcoma is the third most common primary bone cancer, requiring surgical resection. However, differentiation of low-grade chondrosarcoma (grade 1) from enchondroma that is benign and only requires regular follow-up is one of the most frequent diagnostic dilemmas facing orthopedic oncologists in clinical management. Although multiple techniques are applied to make the distinction, immunoh...
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ژورنال
عنوان ژورنال: JCI Insight
سال: 2019
ISSN: 2379-3708
DOI: 10.1172/jci.insight.127232